Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 18/20 | 0.58 |
| ▸ | EEF2K | O00418 | 1/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15637436 | 0.94 | CTSA (0.57) | CTSA | |
| SCHEMBL15637117 | 0.92 | MME (0.52) | CTSAAPLNR | |
| SCHEMBL15637036 | 0.92 | CTSA (0.52) | CTSAAPLNR | |
| SCHEMBL15635939 | 0.92 | CTSA (0.59) | CTSA | |
| SCHEMBL15637384 | 0.91 | CTSA (0.57) | CTSAEEF2K | |
| SCHEMBL15637045 | 0.90 | CTSA (0.59) | CTSA | |
| SCHEMBL16223766 | 0.90 | CTSA (0.59) | CTSA | |
| SCHEMBL15635849 | 0.89 | MME (0.51) | CTSA | |
| SCHEMBL15636006 | 0.89 | CTSA (0.58) | CTSA | |
| SCHEMBL2317278 | 0.89 | CTSA (0.49) | CTSAAPLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |