Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 18/20 | 0.53 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15636531 | 0.97 | CTSA (0.51) | CTSAKMT2A | |
| SCHEMBL15636360 | 0.96 | CTSA (0.49) | CTSAKMT2A | |
| SCHEMBL15636002 | 0.95 | CTSA (0.53) | CTSA | |
| SCHEMBL15636592 | 0.93 | CTSA (0.52) | CTSAKMT2A | |
| SCHEMBL15636640 | 0.92 | CTSA (0.52) | CTSA | |
| SCHEMBL15636656 | 0.91 | CTSA (0.53) | CTSAMMP12 | |
| SCHEMBL15636168 | 0.91 | CTSA (0.57) | CTSAMMP12 | |
| SCHEMBL15636514 | 0.90 | CTSA (0.50) | CTSAKMT2A | |
| SCHEMBL15636448 | 0.90 | CTSA (0.56) | CTSA | |
| SCHEMBL15635626 | 0.90 | CTSA (0.52) | CTSAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |