Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 7/20 | 0.59 |
| ▸ | EGLN2 | Q96KS0 | 9/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15637471 | 0.93 | CTSA (0.52) | CTSAEGLN2EGLN1CYP26A1MME | |
| SCHEMBL15636499 | 0.93 | EGLN2 (0.57) | CTSAEGLN2EGLN1CYP26A1ITGB1 | |
| SCHEMBL15637363 | 0.91 | CTSA (0.53) | CTSAEGLN2EGLN1CYP26A1MME | |
| SCHEMBL2325361 | 0.91 | CTSA (0.55) | CTSACYP26A1MMECYP3A4 | |
| SCHEMBL15635838 | 0.91 | CTSA (0.55) | CTSACYP26A1MMECYP3A4 | |
| SCHEMBL15636881 | 0.89 | EGLN2 (0.53) | CTSAEGLN2EGLN1CYP26A1 | |
| SCHEMBL15636627 | 0.88 | CTSA (0.55) | CTSAEGLN2EGLN1MMECYP3A4 | |
| SCHEMBL15635913 | 0.88 | EGLN2 (0.50) | CTSAEGLN2EGLN1CYP26A1ITGB1 | |
| SCHEMBL15636168 | 0.88 | CTSA (0.57) | CTSACYP26A1 | |
| SCHEMBL15636490 | 0.88 | CYP26A1 (0.50) | CTSACYP26A1ITGB1ITGA4MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |