Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 10/20 | 0.52 |
| ▸ | PRNP | P04156 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | APLNR | P35414 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15636942 | 1.00 | CTSA (0.52) | CTSAPRNPNPSR1RXFP1PTGS2 | |
| SCHEMBL15635884 | 1.00 | CTSA (0.52) | CTSAPRNPNPSR1RXFP1PTGS2 | |
| SCHEMBL15637120 | 0.97 | CTSA (0.50) | CTSAPRNPNPSR1RXFP1PTGS2 | |
| SCHEMBL15637008 | 0.95 | CTSA (0.53) | CTSAPRNPNPSR1RXFP1APLNR | |
| SCHEMBL15636384 | 0.95 | CTSA (0.53) | CTSACYP26A1 | |
| SCHEMBL15637366 | 0.92 | CTSA (0.52) | CTSAPRNPNPSR1RXFP1PTGS2 | |
| SCHEMBL15636963 | 0.92 | CTSA (0.54) | CTSAPRNPNPSR1RXFP1APLNR | |
| SCHEMBL15637296 | 0.92 | CTSA (0.54) | CTSAPRNPNPSR1RXFP1APLNR | |
| SCHEMBL15635631 | 0.92 | CTSA (0.54) | CTSAMEN1KMT2ACYP26A1 | |
| SCHEMBL15636227 | 0.92 | CTSA (0.54) | CTSAMEN1KMT2ACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |