Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 10/20 | 0.56 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.52 |
| ▸ | PDE2A | O00408 | 5/20 | 0.46 |
| ▸ | EEF2K | O00418 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15636351 | 1.00 | CTSA (0.56) | CTSACYP26A1PDE2AEEF2KGRM5 | |
| SCHEMBL15636893 | 0.97 | CTSA (0.53) | CTSACYP26A1PDE2AEEF2KGRM5 | |
| SCHEMBL15635882 | 0.93 | CTSA (0.53) | CTSACYP26A1PDE2A | |
| SCHEMBL15636277 | 0.92 | CTSA (0.49) | CTSACYP26A1GRM5PTGS2 | |
| SCHEMBL15636389 | 0.91 | CTSA (0.55) | CTSACYP26A1 | |
| SCHEMBL15636419 | 0.91 | CTSA (0.54) | CTSACYP26A1PDE2A | |
| SCHEMBL15635942 | 0.90 | CTSA (0.59) | CTSACYP26A1 | |
| SCHEMBL15637392 | 0.90 | CYP26A1 (0.65) | CTSACYP26A1PDE2A | |
| SCHEMBL15637240 | 0.89 | CTSA (0.58) | CTSA | |
| SCHEMBL15636782 | 0.88 | CTSA (0.59) | CTSACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |