Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 6/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15640905 | 1.00 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3MGLLFAAH | |
| SCHEMBL16242384 | 1.00 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3MGLLFAAH | |
| SCHEMBL17633323 | 0.84 | GRIN1 (0.56) | SLC6A2SLC6A4SLC6A3MGLLFAAH | |
| SCHEMBL27076410 | 0.84 | GRIN1 (0.56) | SLC6A2SLC6A4SLC6A3MGLLFAAH | |
| SCHEMBL17633327 | 0.84 | GRIN1 (0.56) | SLC6A2SLC6A4SLC6A3MGLLFAAH | |
| SCHEMBL15640879 | 0.83 | GRIN1 (0.43) | MGLLFAAHGRIN1GRIN2BKDM4E | |
| SCHEMBL16242387 | 0.83 | GRIN1 (0.43) | MGLLFAAHGRIN1GRIN2BKDM4E | |
| SCHEMBL15640880 | 0.83 | GRIN1 (0.43) | MGLLFAAHGRIN1GRIN2BKDM4E | |
| SCHEMBL2117772 | 0.83 | NR1H2 (0.46) | SLC6A2SLC6A4SLC6A3MGLLFAAH | |
| SCHEMBL2112991 | 0.83 | NR1H2 (0.46) | SLC6A2SLC6A4SLC6A3MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430006-B1 | CYCLOPENTA[C]PYRROLE-2-CARBOXYLATE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2014-11-26 | — | — | EP | disclosed |
| US-8697883-B2 | Cyclopenta[C]pyrrole-2-carboxylate derivatives, preparation thereof and therapeutic use thereof | SANOFI (FR) | 2014-04-15 | — | — | US | disclosed |