Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 16/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633192 | 0.92 | TRPV1 (1.00) | TRPV1 | |
| Trifluoroacetic Acid SCHEMBL5632135 | 0.91 | TRPV1 (0.94) | TRPV1 | |
| Trifluoroacetic Acid SCHEMBL5633072 | 0.90 | TRPV1 (0.77) | TRPV1 | |
| Trifluoroacetic Acid SCHEMBL5632164 | 0.90 | TRPV1 (0.89) | TRPV1 | |
| SCHEMBL15679710 | 0.89 | TRPV1 (0.86) | TRPV1 | |
| SCHEMBL4200514 | 0.89 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL4343430 | 0.89 | TRPV1 (0.86) | TRPV1 | |
| Trifluoroacetic Acid SCHEMBL17994154 | 0.89 | TRPV1 (0.89) | TRPV1 | |
| Trifluoroacetic Acid SCHEMBL5634007 | 0.88 | TRPV1 (0.79) | TRPV1 | |
| SCHEMBL15697568 | 0.88 | TRPV1 (1.00) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024368-B1 | 6,7,8,9-TETRAHYDRO-5H-PYRIMIDO[4,5-D]AZEPIN-4-YL]-AMINE DERIVATIVES AS MODULATORS OF TRPV1 FOR THE TREATMENT OF PAIN | JANSSEN PHARMACEUTICA NV (BE) | 2014-04-30 | — | — | EP | claimed |