Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 19/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL15655864 | 0.98 | TRPV1 (0.79) | TRPV1 | |
| SCHEMBL15655161 | 0.96 | TRPV1 (0.76) | TRPV1 | |
| Dimethylcarbate SCHEMBL15656813 | 0.95 | TRPV1 (0.75) | TRPV1 | |
| Carbamic Acid SCHEMBL15653610 | 0.90 | TRPV1 (0.75) | TRPV1 | |
| SCHEMBL4195417 | 0.89 | TRPV1 (0.82) | TRPV1 | |
| SCHEMBL4198471 | 0.88 | TRPV1 (0.75) | TRPV1 | |
| SCHEMBL5632546 | 0.88 | TRPV1 (1.00) | TRPV1 | |
| Bicarbonate SCHEMBL15654476 | 0.87 | TRPV1 (0.76) | TRPV1 | |
| SCHEMBL4197673 | 0.87 | TRPV1 (0.76) | TRPV1 | |
| SCHEMBL4184985 | 0.87 | TRPV1 (0.86) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024368-B1 | 6,7,8,9-TETRAHYDRO-5H-PYRIMIDO[4,5-D]AZEPIN-4-YL]-AMINE DERIVATIVES AS MODULATORS OF TRPV1 FOR THE TREATMENT OF PAIN | JANSSEN PHARMACEUTICA NV (BE) | 2014-04-30 | — | — | EP | claimed |