SCHEMBL15660484

SCHEMBL15660484

CCCCCCP(CCCCCC)c1ccc2ccccc2c1-c1c(P(CCCCCC)CCCCCC)ccc2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.41
KDM4E B2RXH2 4/20 0.41
NPC1 O15118 4/20 0.41
ALDH1A1 P00352 4/20 0.41
HTT P42858 4/20 0.41
RAB9A P51151 4/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
HPGD P15428 1/20 0.41
CYP2C19 P33261 1/20 0.41
MAPK1 P28482 1/20 0.41
RAD52 P43351 1/20 0.41
TLR8 Q9NR97 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15659112 1.00 GAA (0.41) GAAKDM4ENPC1ALDH1A1HTT
SCHEMBL15657877 1.00 GAA (0.41) GAAKDM4ENPC1ALDH1A1HTT
SCHEMBL3265241 0.98 TLR8 (0.40) GAAKDM4ENPC1ALDH1A1HTT
SCHEMBL15658141 0.93 GAA (0.41) GAAKDM4ENPC1ALDH1A1HTT
SCHEMBL29100398 0.88 TLR8 (0.40) GAAKDM4ENPC1ALDH1A1HTT
SCHEMBL15657108 0.86 MAPT (0.40) GAAALDH1A1CYP1A2CYP2C19TLR8
SCHEMBL15656195 0.86 KDM4E (0.43) GAAKDM4ENPC1ALDH1A1HTT
SCHEMBL15658653 0.86 KDM4E (0.43) GAAKDM4ENPC1ALDH1A1HTT
SCHEMBL15657848 0.86 KDM4E (0.43) GAAKDM4ENPC1ALDH1A1HTT
SCHEMBL15656771 0.84 GAA (0.42) GAAKDM4ENPC1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2735581-B1 COMPOSITION AND POLYMER ASAHI CHEMICAL IND (JP) 2021-07-14 EP disclosed
US-9738757-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-08-22 US disclosed
US-20160222168-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-08-04 US disclosed
US-9334371-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-05-10 US disclosed
EP-2735581-A1 COMPOSITION AND POLYMER Asahi Kasei Chemicals Corporation (JP) 2014-05-28 EP disclosed
US-20140121293-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-05-01 US disclosed