SCHEMBL15663427

SCHEMBL15663427

CCOC(=O)ON1CCN(C(=O)[C@H](CCC(=O)O)NC(=O)c2cc(NCCO)cc(-c3ccccc3)n2)CC1

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
P2RY12 Q9H244 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL316582 0.92 P2RY12 (1.00) P2RY12
SCHEMBL316581 0.92 P2RY12 (1.00) P2RY12
SCHEMBL15663931 0.92 P2RY12 (0.71) P2RY12
SCHEMBL15663915 0.89 P2RY12 (0.71) P2RY12
SCHEMBL15663732 0.89 P2RY12 (0.73) P2RY12
SCHEMBL15663460 0.88 P2RY12 (0.82) P2RY12
SCHEMBL15663775 0.87 P2RY12 (0.83) P2RY12
SCHEMBL9993189 0.87 P2RY12 (0.82) P2RY12
SCHEMBL15663967 0.87 P2RY12 (0.82) P2RY12
SCHEMBL9994581 0.87 P2RY12 (0.84) P2RY12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2081903-B1 2-AMINOCARBONYL-PYRIDINE DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2014-05-07 EP claimed