Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15663443 | 0.89 | GRM5 (0.35) | PDE10AGRM5 | |
| SCHEMBL15664555 | 0.89 | GRM5 (0.50) | GRM5 | |
| SCHEMBL15663669 | 0.84 | GRM5 (0.44) | GRM5 | |
| Hydrochloric Acid SCHEMBL17685480 | 0.82 | PDE10A (0.36) | PDE10AGRM5 | |
| SCHEMBL2826292 | 0.81 | GRM5 (0.44) | GRM5 | |
| SCHEMBL15663531 | 0.80 | PDE10A (0.40) | PDE10AGRM5 | |
| SCHEMBL15663486 | 0.80 | PDE10A (0.51) | PDE10AGRM5 | |
| SCHEMBL15663452 | 0.80 | GRM5 (0.52) | PDE10AGRM5 | |
| SCHEMBL15663871 | 0.80 | PDE10A (0.36) | PDE10AGRM5 | |
| SCHEMBL15663562 | 0.79 | GRM5 (0.43) | PDE10AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858854-B1 | PYRIDINE-2-CARBOXAMIDE DERIVATIVES AS MGLUR5 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2014-05-07 | — | — | EP | claimed |