Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30353903 | 0.83 | SRC (0.48) | SRCDHFRKMT2APARP1EGFR | |
| SCHEMBL6912846 | 0.83 | SRC (0.48) | SRCDHFRKMT2APARP1EGFR | |
| SCHEMBL30353891 | 0.79 | SRC (0.45) | SRCDHFRKMT2APARP1EGFR | |
| SCHEMBL20546993 | 0.79 | SRC (0.45) | SRCDHFRKMT2APARP1EGFR | |
| SCHEMBL6912439 | 0.79 | SRC (0.45) | SRCDHFRKMT2APARP1EGFR | |
| SCHEMBL1468319 | 0.75 | TNF (0.46) | SRCDHFRKMT2APARP1POLB | |
| SCHEMBL615784 | 0.71 | PDE3B (0.50) | SRCKMT2APARP1KDM4ENPC1 | |
| SCHEMBL29609262 | 0.71 | PDE3B (0.50) | SRCKMT2APARP1KDM4ENPC1 | |
| SCHEMBL13659569 | 0.70 | PARP1 (0.50) | SRCKMT2APARP1PDPK1SMN1; SMN2 | |
| SCHEMBL15710544 | 0.70 | PARP1 (0.44) | SRCKMT2APARP1EGFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014068388-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2014-05-08 | — | — | WO | disclosed |