⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL15649214 | 0.97 | — | — | |
| SCHEMBL1394522 | 0.67 | — | — | |
| Bromide SCHEMBL21807132 | 0.63 | — | — | |
| Bromide SCHEMBL1394442 | 0.63 | — | — | |
| Bromide SCHEMBL21807131 | 0.60 | — | — | |
| SCHEMBL22908211 | 0.60 | — | — | |
| SCHEMBL17752777 | 0.60 | MEN1 (0.35) | — | |
| SCHEMBL17059168 | 0.59 | — | — | |
| SCHEMBL183955 | 0.58 | CRBN (0.44) | — | |
| SCHEMBL4730800 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150246025-A1 | 2-PHENYL-5-HETEROCYCLYL-TETRAHYDRO-2H-PYRAN-3-AMINE COMPOUNDS FOR USE IN THE TREATMENT OF DIABETES AND ITS ASSOCIATED DISORDERS | CADILA HEALTHCARE LIMITED (IN) | 2015-09-03 | — | — | US | disclosed |
| WO-2014061031-A1 | 2-PHENYL-5-HETEROCYCLYL-TETRAHYDRO-2H-PYRAN-3-AMINE COMPOUNDS FOR USE IN THE TREATMENT OF DIABETES AND ITS ASSOCIATED DISORDERS | CADILA HEALTHCARE LIMITED (IN) | 2014-04-24 | — | — | WO | disclosed |