Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CALCA | P06881 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19349361 | 0.91 | MAP3K11 (0.46) | MAP3K11PLK4AKR1B1AURKADAPK3 | |
| SCHEMBL15690378 | 0.88 | MAP3K11 (0.50) | MAP3K11PLK4AKR1B1AURKADAPK3 | |
| SCHEMBL30088104 | 0.88 | MAP3K11 (0.53) | MAP3K11PLK4AKR1B1AURKADAPK3 | |
| SCHEMBL15999434 | 0.88 | MAP3K11 (0.53) | MAP3K11PLK4AKR1B1AURKADAPK3 | |
| SCHEMBL15999428 | 0.86 | MAP3K11 (0.52) | MAP3K11PLK4AKR1B1AURKADAPK3 | |
| SCHEMBL21920772 | 0.85 | MAP3K11 (0.42) | MAP3K11PLK4AKR1B1AURKADAPK3 | |
| SCHEMBL15690242 | 0.84 | MAP3K11 (0.41) | MAP3K11PLK4AKR1B1AURKADAPK3 | |
| SCHEMBL31349435 | 0.82 | MAP3K11 (0.42) | MAP3K11BACE1AKR1B1CALCAFGFR1 | |
| SCHEMBL15117493 | 0.79 | MAP3K11 (0.41) | MAP3K11BACE1CALCAOPRM1 | |
| SCHEMBL15117477 | 0.78 | MAP3K11 (0.40) | MAP3K11BACE1CALCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014072930-A2 | FUSED PYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-05-15 | — | — | WO | disclosed |