Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 7/20 | 0.53 |
| ▸ | CYP2C8 | P10632 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TEK | Q02763 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | RAF1 | P04049 | 3/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15701292 | 1.00 | CYP2C9 (0.53) | CYP2C9CYP2C8CYP2D6TEKKDR | |
| SCHEMBL15701290 | 1.00 | CYP2C9 (0.53) | CYP2C9CYP2C8CYP2D6TEKKDR | |
| SCHEMBL19446744 | 0.94 | CYP2C9 (0.53) | CYP2C9CYP2C8CYP2D6TEKKDR | |
| SCHEMBL15701279 | 0.88 | GRM1 (0.43) | CYP2C9CYP2C8TEKKDRRAF1 | |
| SCHEMBL15701109 | 0.88 | GRM1 (0.43) | CYP2C9CYP2C8TEKKDRRAF1 | |
| SCHEMBL15701105 | 0.88 | GRM1 (0.43) | CYP2C9CYP2C8TEKKDRRAF1 | |
| SCHEMBL15701286 | 0.86 | PSEN1 (0.44) | CYP2C9CYP2C8RAF1BRAFCSNK1D | |
| SCHEMBL15701107 | 0.86 | PSEN1 (0.44) | CYP2C9CYP2C8RAF1BRAFCSNK1D | |
| SCHEMBL15701291 | 0.86 | PSEN1 (0.44) | CYP2C9CYP2C8RAF1BRAFCSNK1D | |
| SCHEMBL15701083 | 0.83 | CYP2C9 (0.49) | CYP2C9CYP2C8CYP2D6TEKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334249-B2 | Inhibitors of cytomegalovirus | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-05-10 | — | — | US | disclosed |
| US-20150284348-A1 | INHIBITORS OF CYTOMEGALOVIRUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
| WO-2014070979-A1 | INHIBITORS OF CYTOMEGALOVIRUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284348-A1 | INHIBITORS OF CYTOMEGALOVIRUS | CDKN1A, CCNA1, IFNAR1 | CYP2C9 2373/4885CYP2C8 2028/4885CYP2D6 3355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.