Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 8/20 | 0.53 |
| ▸ | CYP2C8 | P10632 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CBLB | Q13191 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17147291 | 0.84 | CYP2C9 (0.55) | CYP2C9CYP2C8KMT2ACYP3A4CYP2D6 | |
| SCHEMBL17147290 | 0.84 | CYP2C9 (0.55) | CYP2C9CYP2C8KMT2ACYP3A4CYP2D6 | |
| SCHEMBL15701042 | 0.84 | CYP2C9 (0.55) | CYP2C9CYP2C8KMT2ACYP3A4CYP2D6 | |
| SCHEMBL15701088 | 0.82 | CYP3A4 (0.52) | CYP2C9KMT2ACYP3A4CYP2D6MEN1 | |
| SCHEMBL15701089 | 0.81 | CNR1 (0.53) | CYP2C9CYP2C8KMT2ACYP3A4CYP2D6 | |
| SCHEMBL15701265 | 0.80 | PSEN1 (0.50) | CYP2C9KMT2ACYP3A4CYP2D6MEN1 | |
| SCHEMBL7075380 | 0.79 | CYP2C9 (0.49) | CYP2C9CYP2C8KMT2ACYP3A4CYP2D6 | |
| SCHEMBL15701097 | 0.78 | RIOK2 (0.56) | CYP2C9KMT2ACYP3A4CYP2D6MEN1 | |
| SCHEMBL7908147 | 0.78 | CYP2C9 (0.47) | CYP2C9CYP2C8KMT2ACYP3A4CYP2D6 | |
| SCHEMBL7743967 | 0.78 | CYP2C9 (0.47) | CYP2C9CYP2C8KMT2ACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914592-B1 | INHIBITORS OF CYTOMEGALOVIRUS | BOEHRINGER INGELHEIM INT (DE) | 2017-10-11 | — | — | EP | disclosed |
| US-9334249-B2 | Inhibitors of cytomegalovirus | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-05-10 | — | — | US | disclosed |
| US-20150284348-A1 | INHIBITORS OF CYTOMEGALOVIRUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
| WO-2014070979-A1 | INHIBITORS OF CYTOMEGALOVIRUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284348-A1 | INHIBITORS OF CYTOMEGALOVIRUS | CDKN1A, CCNA1, IFNAR1 | CYP2C9 2373/4885CYP2C8 2028/4885KMT2A 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.