Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14061120 | 0.93 | BCL2 (0.78) | BCL2BCL2L1 | |
| SCHEMBL16846604 | 0.93 | BCL2 (0.78) | BCL2BCL2L1 | |
| SCHEMBL14061190 | 0.89 | BCL2 (0.78) | BCL2BCL2L1 | |
| SCHEMBL16846601 | 0.88 | BCL2 (0.82) | BCL2BCL2L1 | |
| SCHEMBL14061127 | 0.87 | BCL2 (1.00) | BCL2BCL2L1 | |
| SCHEMBL14149568 | 0.86 | BCL2 (0.79) | BCL2BCL2L1 | |
| SCHEMBL14061313 | 0.86 | BCL2 (1.00) | BCL2BCL2L1 | |
| SCHEMBL15701744 | 0.86 | BCL2 (0.81) | BCL2BCL2L1 | |
| SCHEMBL14061563 | 0.85 | BCL2 (1.00) | BCL2BCL2L1 | |
| SCHEMBL15675392 | 0.84 | BCL2 (0.95) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346795-B2 | Substituted sulfonamides useful as antiapoptotic Bcl inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |
| US-20140135318-A1 | SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135318-A1 | SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS | BCL2, BAX, BCL2A1 | BCL2 1/4885BCL2L1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.