⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423168 | 1.00 | — | — | |
| SCHEMBL1649846 | 1.00 | — | — | |
| SCHEMBL30825842 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL28666719 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL29902444 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL28835468 | 0.96 | — | — | |
| SCHEMBL9632104 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL28673558 | 0.96 | GABRR1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL29902442 | 0.96 | — | — | |
| SCHEMBL29223401 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113816858-B | Preparation method of trans-1, 2-diaminomethylcyclobutane and hydrochloride thereof | 四川汇宇制药股份有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-115032297-A | Separation and detection method of trans-1, 2-diaminomethylcyclobutane and cis-isomer thereof | 四川汇宇制药股份有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-113816858-A | Preparation method of trans-1, 2-diaminomethylcyclobutane and hydrochloride thereof | 四川汇宇制药股份有限公司 | 2021-12-21 | — | — | CN | claimed |
| CN-115032297-B | Separation detection method of trans-1, 2-diaminomethyl cyclobutane and cis isomer thereof | 四川汇宇制药股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-113816858-B | Preparation method of trans-1, 2-diaminomethylcyclobutane and hydrochloride thereof | 四川汇宇制药股份有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-113816858-B | Preparation method of trans-1, 2-diaminomethylcyclobutane and hydrochloride thereof | 四川汇宇制药股份有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-113816858-B | Preparation method of trans-1, 2-diaminomethylcyclobutane and hydrochloride thereof | 四川汇宇制药股份有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-115032297-A | Separation and detection method of trans-1, 2-diaminomethylcyclobutane and cis-isomer thereof | 四川汇宇制药股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-115032297-A | Separation and detection method of trans-1, 2-diaminomethylcyclobutane and cis-isomer thereof | 四川汇宇制药股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-115032297-A | Separation and detection method of trans-1, 2-diaminomethylcyclobutane and cis-isomer thereof | 四川汇宇制药股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-113816858-A | Preparation method of trans-1, 2-diaminomethylcyclobutane and hydrochloride thereof | 四川汇宇制药股份有限公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-113816858-A | Preparation method of trans-1, 2-diaminomethylcyclobutane and hydrochloride thereof | 四川汇宇制药股份有限公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-113816858-A | Preparation method of trans-1, 2-diaminomethylcyclobutane and hydrochloride thereof | 四川汇宇制药股份有限公司 | 2021-12-21 | — | — | CN | disclosed |
| EP-2740738-B1 | PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASE, PREPARATION METHODS AND USES THEREOF | BEIJING FSWELCOME TECH DEVELOPMENT CO LTD (CN) | 2018-03-28 | — | — | EP | disclosed |
| US-9138421-B2 | Platinum compounds for treating cell proliferative diseases, preparation method and use thereof | BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2015-09-22 | — | — | US | disclosed |
| EP-2740738-A1 | PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASE, PREPARATION METHODS AND USES THEREOF | Beijing FSwelcome Technology Development Co., Ltd. (CN) | 2014-06-11 | — | — | EP | disclosed |
| US-20140142079-A1 | PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASES, PREPARATION METHOD AND USE THEREOF | BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2014-05-22 | — | — | US | disclosed |