Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 3/20 | 0.68 |
| ▸ | RBBP4 | Q09028 | 3/20 | 0.68 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.68 |
| ▸ | AEBP2 | Q6ZN18 | 3/20 | 0.68 |
| ▸ | EZH2 | Q15910 | 18/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15710954 | 0.91 | EED (0.70) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL17797285 | 0.91 | EED (0.72) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL15710225 | 0.91 | EED (0.72) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL15710270 | 0.91 | EED (0.71) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL15710082 | 0.91 | EED (0.71) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL15710224 | 0.89 | EED (0.67) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL17797303 | 0.89 | EED (0.69) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL17797295 | 0.88 | EZH2 (0.68) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL18222690 | 0.88 | EED (0.68) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL15709898 | 0.88 | EZH2 (0.67) | EEDRBBP4SUZ12AEBP2EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376422-B2 | Dihidropyridin-2-one benzamine compounds | Epizyme, Inc. (US) | 2016-06-28 | — | — | US | disclosed |
| US-20140142083-A1 | Substituted Benzene Compounds | Epizyme, Inc. (US) | 2014-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142083-A1 | Substituted Benzene Compounds | CYP1B1, TP53, VHL | EED 1592/4885RBBP4 253/4885SUZ12 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.