Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | SELL | P14151 | 3/20 | 0.41 |
| ▸ | SELP | P16109 | 3/20 | 0.41 |
| ▸ | SELE | P16581 | 3/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15702040 | 1.00 | GLP1R (0.53) | GLP1RMAPK1ESR1PGRHTR1A | |
| SCHEMBL24239566 | 1.00 | GLP1R (0.53) | GLP1RMAPK1ESR1PGRHTR1A | |
| SCHEMBL17519200 | 1.00 | GLP1R (0.53) | GLP1RMAPK1ESR1PGRHTR1A | |
| SCHEMBL24239564 | 1.00 | GLP1R (0.53) | GLP1RMAPK1ESR1PGRHTR1A | |
| SCHEMBL24453710 | 0.97 | MAPK1 (0.56) | GLP1RMAPK1ESR1PGRHTR1A | |
| SCHEMBL24155697 | 0.97 | MAPK1 (0.56) | GLP1RMAPK1ESR1PGRHTR1A | |
| SCHEMBL24696426 | 0.97 | MAPK1 (0.56) | GLP1RMAPK1ESR1PGRHTR1A | |
| SCHEMBL17519197 | 0.97 | MAPK1 (0.56) | GLP1RMAPK1ESR1PGRHTR1A | |
| SCHEMBL24239603 | 0.97 | MAPK1 (0.56) | GLP1RMAPK1ESR1PGRHTR1A | |
| SCHEMBL24239602 | 0.97 | MAPK1 (0.56) | GLP1RMAPK1ESR1PGRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3147367-A1 | SMALL MOLECULE CONJUGATES FOR INTRACELLULAR DELIVERY OF NUCLEIC ACIDS | F. Hoffmann-La Roche AG (CH) | 2017-03-29 | — | — | EP | disclosed |
| US-20140135381-A1 | Small molecule conjugates for intracellular delivery of biologically active compounds | HOFFMANN-LA ROCHE INC. (US) | 2014-05-15 | — | — | US | disclosed |
| US-20140135381-A1 | Small molecule conjugates for intracellular delivery of biologically active compounds | HOFFMANN-LA ROCHE INC. (US) | 2014-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135381-A1 | Small molecule conjugates for intracellular delivery of biologically active compounds | SNRPE, PHAX, SNRPA | GLP1R 4697/4885MAPK1 3839/4885ESR1 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.