SCHEMBL15713293

SCHEMBL15713293

C[SiH](O)CCCOCCO

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
MAPK1 P28482 1/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
THRB P10828 1/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 1/20 0.46
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17675765 0.91 TSHR (0.41) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL3838331 0.83 TSHR (0.54) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL19503984 0.79 MEN1 (0.31) TSHRMEN1KMT2ATHRBHTT
SCHEMBL2851474 0.77 TSHR (0.48) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL6828573 0.76 MEN1 (0.47) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL14826032 0.74 CES1 (0.32)
SCHEMBL11502257 0.74 TSHR (0.30) TSHR
SCHEMBL23210 0.73 TSHR (0.77) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL10937926 0.73 TSHR (0.77) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL651261 0.73 TSHR (0.77) TSHRMAPK1MEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140135422-A1 FOULING CONTROL COATING COMPOSITIONS HEMPEL A/S (DK) 2014-05-15 US disclosed