SCHEMBL15713992

SCHEMBL15713992

C=Cc1ccc(C(=O)NC[C@@H](O)C[C@@H](Cc2ccccc2)C(=CC)N[C@H]2c3ccccc3C[C@H]2O)cc1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
VIPR2 P41587 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15714636 0.91 VIPR2 (0.62) VIPR2
SCHEMBL17038231 0.81 VIPR2 (0.64) VIPR2
SCHEMBL15714139 0.81 VIPR2 (0.74) VIPR2
SCHEMBL15713507 0.79 VIPR2 (0.63) VIPR2
SCHEMBL15713990 0.78 VIPR2 (0.76) VIPR2
SCHEMBL17038232 0.78 VIPR2 (0.62) VIPR2
SCHEMBL15714630 0.76 VIPR2 (0.82) VIPR2
SCHEMBL17038236 0.76 VIPR2 (0.69) VIPR2
SCHEMBL17038228 0.75 VIPR2 (0.60) VIPR2
SCHEMBL17038235 0.75 VIPR2 (0.59) VIPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014075096-A1 INHIBITORS OF CENTRAL NERVOUS SYSTEM VASOACTIVE INHIBITORY PEPTIDE RECEPTOR 2 THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2014-05-15 WO disclosed