Canagliflozin Anhydrous

Canagliflozin Anhydrous

SCHEMBL157162

Cc1ccc([C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1Cc1ccc(-c2ccc(F)cc2)s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Canagliflozin Anhydrous. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC5A2 known ✓ P31639 20/20 1.00
SLC5A1 P13866 6/20 1.00
ABCB11 O95342 1/20 1.00
ADORA3 P0DMS8 1/20 1.00
SLC6A4 P31645 1/20 1.00
SLC6A3 Q01959 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Canagliflozin Anhydrous SCHEMBL19293442 1.00 SLC5A2 (1.00) SLC5A2SLC5A1ABCB11ADORA3SLC6A4
Canagliflozin Anhydrous SCHEMBL16075101 1.00 SLC5A2 (1.00) SLC5A2SLC5A1ABCB11ADORA3SLC6A4
Canagliflozin Anhydrous SCHEMBL19493514 1.00 SLC5A2 (1.00) SLC5A2SLC5A1ABCB11ADORA3SLC6A4
Canagliflozin Anhydrous SCHEMBL873848 1.00 SLC5A2 (1.00) SLC5A2SLC5A1ABCB11ADORA3SLC6A4
Canagliflozin Anhydrous SCHEMBL19493519 1.00 SLC5A2 (1.00) SLC5A2SLC5A1ABCB11ADORA3SLC6A4
Canagliflozin Anhydrous SCHEMBL24037935 1.00 SLC5A2 (1.00) SLC5A2SLC5A1ABCB11ADORA3SLC6A4
Canagliflozin Anhydrous SCHEMBL16421559 1.00 SLC5A2 (1.00) SLC5A2SLC5A1ABCB11ADORA3SLC6A4
Canagliflozin Anhydrous SCHEMBL13695263 1.00 SLC5A2 (1.00) SLC5A2SLC5A1ABCB11ADORA3SLC6A4
Canagliflozin Anhydrous SCHEMBL15888791 1.00 SLC5A2 (1.00) SLC5A2SLC5A1ABCB11ADORA3SLC6A4
Canagliflozin Anhydrous SCHEMBL19293553 1.00 SLC5A2 (1.00) SLC5A2SLC5A1ABCB11ADORA3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5318 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746887-A1 METHODS OF TREATING CHRONIC KIDNEY DISEASE (CKD) OR CKD AND HYPERTENSION WITH LORUNDROSTAT, OR A COMBINATION OF LORUNDROSTAT AND A SGLT2 INHIBITOR Mineralys Therapeutics, Inc. (US) 2026-05-27 EP claimed
CN-122055157-A Method for reducing the risk of cardiovascular events in patients with left ventricular hypertrophy 莱西肯医药有限公司 2026-05-15 CN claimed
EP-4736842-A1 IN SITU GEL FORMULATION AND PREPARATION METHOD THEREOF ANXO Pharmaceutical Co., Ltd. (TW) 2026-05-06 EP claimed
WO-2026087680-A1 TREATMENT FOR CARDIOVASCULAR DISEASE SAPREME TECHNOLOGIES B.V. (NL) 2026-04-30 WO claimed
WO-2026087695-A1 TREATMENT FOR METABOLIC DISORDER SAPREME TECHNOLOGIES B.V. (NL) 2026-04-30 WO claimed
EP-3634453-B1 PLANT EXTRACTS WITH ANTI-DIABETIC AND OTHER USEFUL ACTIVITIES HOUSEY PHARMACEUTICAL RES LABORATORIES L L C (US) 2026-04-29 EP claimed
EP-4729635-A2 DIAGNOSIS AND TREATMENT OF NAFLD AND LIVER FIBROSIS Beth Israel Deaconess Medical Center, Inc. (US) 2026-04-22 EP claimed
EP-4727528-A1 A PHARMACEUTICAL FORMULATION COMPRISING LINAGLIPTIN, METFORMIN AND A SGLT-2 INHIBITOR Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi (TR) 2026-04-22 EP claimed
EP-4724042-A1 METHOD FOR IMPROVING THE INGESTION OF A LIQUID OR VISCOUS SUBSTANCE Ceva Santé Animale (FR) 2026-04-15 EP claimed
EP-4719429-A1 COMBINATION TREATMENT AND/OR PREVENTION OF CARDIAC DISEASES IN NON-HUMAN MAMMALS COMPRISING ONE OR MORE SGLT-2 INHIBITORS AND PIMOBENDAN AND/OR TELMISARTAN Boehringer Ingelheim Vetmedica GmbH (DE) 2026-04-08 EP claimed
CN-101784286-A Pharmaceutical composition comprising a sglt2 inhibitor in combination with a dpp-iv inhibitor BOEHRINGER INGELHEIM INT 2010-07-21 CN claimed
EP-2187966-A1 PHARMACEUTICAL COMPOSITION COMPRISING A SGLT2 INHIBITOR IN COMBINATION WITH A DPP-IV INHIBITOR Boehringer Ingelheim International GmbH (DE) 2010-05-26 EP claimed
EP-2102224-A1 CRYSTALLINE FORM OF 1- (ß-D-GLUCOPYRANOSYL) -4 -METHYL- 3- [5- (4 -FLUOROPHENYL) -2-THIENYLMETHYL]BENZENE HEMIHYDRATE Mitsubishi Tanabe Pharma Corporation (JP) 2009-09-23 EP claimed
WO-2009022010-A1 PHARMACEUTICAL COMPOSITION COMPRISING A SGLT2 INHIBITOR IN COMBINATION WITH A DPP-IV INHIBITOR BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-02-19 WO claimed
US-20080146515-A1 Crystalline form of 1-(beta-D-glucopyransoyl)-4-methyl-3-[5-(4-fluorophenyl)-2- thienylmethyl]benzene hemihydrate MITSUBISHI TANABE PHARMA CORPORATION (JP) 2008-06-19 US claimed
WO-2008069327-A1 CRYSTALLINE FORM OF 1- (β-D-GLUCOPYRANOSYL) -4 -METHYL- 3- [5- (4 -FLUOROPHENYL) -2-THIENYLMETHYL] BENZENE HEMIHYDRATE MITSUBISHI TANABE PHARMA CORPORATION (JP) 2008-06-12 WO claimed
CN-1829729-A Novel compounds TANABE SEIYAKU CO (JP) 2006-09-06 CN claimed
EP-1651658-A1 NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT TRANSPORTER TANABE SEIYAKU CO., LTD. (JP) 2006-05-03 EP claimed
US-20050233988-A1 Novel compounds TANABE SEIYAKU CO., LTD. (JP) 2005-10-20 US claimed
WO-2005012326-A1 NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT TRANSPORTER TANABE SEIYAKU CO., LTD. (JP) 2005-02-10 WO claimed