Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLA1 | P09884 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | CDA | P32320 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13160995 | 1.00 | PDE4D (0.55) | PDE4DPDE3ASLC29A1LMNAPOLA1 | |
| SCHEMBL15675815 | 0.99 | PDE4D (0.54) | PDE4DPDE3ASLC29A1LMNAPOLA1 | |
| SCHEMBL15675784 | 0.99 | PDE4D (0.54) | PDE4DPDE3ASLC29A1LMNAPOLA1 | |
| SCHEMBL15675962 | 0.97 | PDE4D (0.56) | PDE4DPDE3ASLC29A1LMNAPOLA1 | |
| SCHEMBL19698969 | 0.97 | PDE4D (0.56) | PDE4DPDE3ASLC29A1LMNAPOLA1 | |
| SCHEMBL23700177 | 0.95 | PDE4D (0.50) | PDE4DPDE3ASLC29A1LMNAPOLA1 | |
| SCHEMBL18759734 | 0.92 | PDE4D (0.46) | PDE4DPDE3ASLC29A1LMNAPOLA1 | |
| SCHEMBL13160999 | 0.91 | POLA1 (0.48) | PDE4DPDE3ASLC29A1LMNAPOLA1 | |
| SCHEMBL13161034 | 0.91 | POLA1 (0.48) | PDE4DPDE3ASLC29A1LMNAPOLA1 | |
| SCHEMBL13160971 | 0.90 | PDE4D (0.60) | PDE4DPDE3ASLC29A1LMNAPOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2919790-A1 | GEMCITABINE PRODRUGS AND USES THEREOF | Boyen Therapeutics, Inc. (TW) | 2015-09-23 | — | — | EP | disclosed |
| WO-2014078295-A1 | GEMCITABINE PRODRUGS AND USES THEREOF | BoYen Therapeutics, Inc. (TW) | 2014-05-22 | — | — | WO | disclosed |