SCHEMBL157176

SCHEMBL157176

[CH2]C(CO)CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6749363 0.79
SCHEMBL20237102 0.76
SCHEMBL20529116 0.76
SCHEMBL2477687 0.76
SCHEMBL1761341 0.76
SCHEMBL902401 0.76
SCHEMBL1033934 0.74
SCHEMBL28743805 0.73
SCHEMBL9751306 0.73
SCHEMBL11037372 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3134 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167342-A1 POLYOL COMPOUNDS AND ADHESIVE COMPOSITIONS PREPARED WITH THE SAME ARKEMA FRANCE (FR) 2023-06-01 US claimed
EP-3344630-B1 SUBSTITUTED 1,2-DIHYDRO-3H-PYRROLO[1,2-C]IMIDAZOL-3-ONE ANTIBACTERIAL COMPOUNDS IDORSIA PHARMACEUTICALS LTD (CH) 2020-12-09 EP claimed
US-20190315731-A1 6-(BUTA-1,3-DIYN-1-YL)BENZO[D]THIAZOLE DERIVATIVES ACTELION PHARMACEUTICALS, LTD. (CH) 2019-10-17 US claimed
US-10314823-B2 Substituted 1,2-dihydro-3H-pyrrolo[1,2-c]imidazol-3-one antibacterial compounds IDORSIA PHARMACEUTICALS LTD (CH) 2019-06-11 US claimed
EP-2974713-B1 CERAMIDE-LIKE FUNCTION IMPARTING AGENT KAO CORP (JP) 2019-05-01 EP claimed
EP-3458453-A1 6-(BUTA-1,3-DIYN-1-YL)BENZO[D]THIAZOLE DERIVATIVES Idorsia Pharmaceuticals Ltd (CH) 2019-03-27 EP claimed
EP-3033343-B1 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF MEK NOVARTIS AG (CH) 2018-12-05 EP claimed
US-10143667-B2 Ceramide-like function imparting agent KAO CORPORATION (JP) 2018-12-04 US claimed
US-20180250273-A1 SUBSTITUTED 1,2-DIHYDRO-3H-PYRROLO[1,2-c]IMIDAZOL-3-ONE ANTIBACTERIAL COMPOUNDS IDORSIA PHARMACEUTICALS LTD. (CH) 2018-09-06 US claimed
EP-3344630-A1 SUBSTITUTED 1,2-DIHYDRO-3H-PYRROLO[1,2-C]IMIDAZOL-3-ONE ANTIBACTERIAL COMPOUNDS Idorsia Pharmaceuticals Ltd (CH) 2018-07-11 EP claimed
US-20040077646-A1 Indole nitriles ROCHE PALO ALTO LLC 2004-04-22 US claimed
US-20030199691-A1 2-(2,6-dichlorophenyl)-diarylimidazoles F. HOFFMANN-LA ROCHE AG (CH) 2003-10-23 US claimed
WO-2003087026-A1 2-(2,6-DICHLOROPHENYL)-DIARYLIMIDAZOLES F. HOFFMANN-LA ROCHE AG (CH) 2003-10-23 WO claimed
EP-1341412-A1 INDOLOCARBAZOLE ANTICANCER AGENTS AND METHODS OF USING THEM Advanced Life Sciences, Inc. (US) 2003-09-10 EP claimed
US-6605596-B2 Topoisomerase I inhibitors ADVANCED LIFE SCIENCES, INC. 2003-08-12 US claimed
US-20030087842-A1 Indolocarbazole anticancer agents and methods of using them ADVANCED LIFE SCIENCES, INC. 2003-05-08 US claimed
WO-2002048166-A1 INDOLOCARBAZOLE ANTICANCER AGENTS AND METHODS OF USING THEM ADVANCED LIFE SCIENCES, INC. (US) 2002-06-20 WO claimed
US-5753660-A Substituted sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors G. D. SEARLE & CO. (US) 1998-05-19 US claimed
US-5106958-A For dyeing or printing organic substrates SANDOZ LTD. (CH) 1992-04-21 US claimed
US-5004835-A Substituted dicarboxylic acid-bis(3,5-dicarbamoyl-2,4,6-triiodoanilides), process for their production as well as X-ray contrast media containing them SCHERING AKTIENGESELLSCHAFT (DE) 1991-04-02 US claimed