SCHEMBL157189

SCHEMBL157189

[CH2]CC#CCCCCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1038888 0.97 PTPN7 (0.50)
SCHEMBL1117101 0.97 PTPN7 (0.50)
SCHEMBL313546 0.97 PTPN7 (0.50)
SCHEMBL10949267 0.97 PTPN7 (0.50)
SCHEMBL7994732 0.97 PTPN7 (0.50)
SCHEMBL9514818 0.97 PTPN7 (0.50)
SCHEMBL154494 0.97 PTPN7 (0.50)
SCHEMBL3866734 0.97 PTPN7 (0.50)
SCHEMBL9515428 0.97 PTPN7 (0.50)
SCHEMBL313624 0.97 PTPN7 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1784 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120232105-A1 PHARMACEUTICAL COMPOSITION FOR INHIBITING OSTEOCLAST GROWTH NATIONAL DEFENSE MEDICAL CENTER (TW) 2012-09-13 US claimed
WO-2024149331-A1 AMINO LIPID COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 深圳深信生物科技有限公司 2024-07-18 WO disclosed
WO-2024149360-A1 BIQUATERNARY AMMONIUM SALT COMPOUND AND PHARMACEUTICAL APPLICATION THEREOF 西藏海思科制药有限公司 2024-07-18 WO disclosed
WO-2024149349-A1 COMPOUND TARGETING POLθ AND USE THEREOF 西藏海思科制药有限公司 2024-07-18 WO disclosed
US-12037439-B2 Water-based polymer hydrogel system IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-07-16 US disclosed
CN-118339168-A Fused ring heterocyclic derivative and application thereof in medicine 西藏海思科制药有限公司 2024-07-12 CN disclosed
WO-2024146559-A1 PYRIDAZINONE HETEROCYCLIC COMPOUND MYOSIN II INHIBITOR AND USE THEREOF 西藏海思科制药有限公司 2024-07-11 WO disclosed
WO-2024146632-A1 TETRAHYDROTHIOPHENE DERIVATIVE AND USE THEREOF IN MEDICINE 西藏海思科制药有限公司 2024-07-11 WO disclosed
EP-4397661-A1 COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2024-07-10 EP disclosed
US-12024511-B2 Substituted imidazo[1,2-a]pyridin-2-ylamine compounds, and pharmaceutical compositions and methods of use thereof SHANGHAI FUDAN-ZHANGJIANG BIO-PHARMACEUTICAL CO., LTD. (CN) 2024-07-02 US disclosed
US-4647585-A Bicycloheptane substituted ethers E. R. SQUIBB & SONS, INC. (US) 1987-03-03 US disclosed
EP-0210664-A2 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs E.R. Squibb &amp; Sons, Inc. (US) 1987-02-04 EP disclosed
US-4638012-A 7-oxabicycloheptane α-substituted ketone prostaglandin analogs useful in the treatment of thrombotic disease E. R. SQUIBB & SONS, INC. (US) 1987-01-20 US disclosed
EP-0207684-A2 7-Oxabicycloheptane substituted diamide and its congener prostaglandin analogs E.R. Squibb &amp; Sons, Inc. (US) 1987-01-07 EP disclosed
EP-0205834-A1 7-Thiabicycloheptane substituted ethers E.R. Squibb &amp; Sons, Inc. (US) 1986-12-30 EP disclosed
US-4611007-A 7-oxabicycloheptane substituted prostaglandin analogs useful in the treatment of thrombotic disease E. R. SQUIBB & SONS, INC. (US) 1986-09-09 US disclosed
US-4611006-A 5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the treatment of thrombotic disease E. R. SQUIBB & SONS, INC. (US) 1986-09-09 US disclosed
US-4608386-A ASTHMA E. R. SQUIBB & SONS, INC. (US) 1986-08-26 US disclosed
US-4595692-A 7-thiabicycloheptane substituted ethers E. R. SQUIBB & SONS, INC. (US) 1986-06-17 US disclosed
US-3944666-A Insecticidal compositions and methods of combatting insects using 3-phenoxybenzyl 2,2-dimethyl-3-(2,2-dichlorovinyl)-cyclopropanecarboxylate insecticide with a synergistic compound of mono (alkyl and alkenyl)mono omega-alkynyl arylphosphonates FMC CORPORATION (US) 1976-03-16 US disclosed