Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.53 |
| ▸ | HCRTR2 | O43614 | 17/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1572525 | 0.93 | HCRTR1 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL1572380 | 0.93 | HCRTR1 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL1571806 | 0.92 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL1571999 | 0.85 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL1572412 | 0.85 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL1572136 | 0.84 | HCRTR1 (0.46) | HCRTR1HCRTR2PKMNPSR1 | |
| SCHEMBL1572548 | 0.84 | HCRTR1 (0.46) | HCRTR1HCRTR2PKMNPSR1 | |
| SCHEMBL1339660 | 0.84 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL1571802 | 0.82 | HCRTR1 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL1572250 | 0.82 | HCRTR1 (0.54) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094690-B1 | 2-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-04-13 | — | — | EP | disclosed |