Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 8/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15966639 | 0.89 | SMN1; SMN2 (0.69) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL15966638 | 0.89 | SMN1; SMN2 (0.69) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL15722117 | 0.87 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL15703388 | 0.87 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL1701200 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL27895527 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL15722122 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL15722123 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL28968951 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL28968948 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567336-B2 | Conjugated TLR7 and/or TLR8 and TLR2 agonists | INVIVOGEN (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9295732-B2 | Conjugated TLR7 and/or TLR8 and TLR2 polycationic agonists | INVIVOGEN (FR) | 2016-03-29 | — | — | US | disclosed |
| US-20140242108-A1 | Conjugated TLR7 and/or TLR8 and TLR2 polycationic agonists | CAYLA (FR) | 2014-08-28 | — | — | US | disclosed |
| EP-2769738-A1 | Conjugated TLR7 and/or TLR8 and TLR2 polycationic agonists | Invivogen (FR) | 2014-08-27 | — | — | EP | disclosed |
| US-20140141033-A1 | CONJUGATED TLR7 AND/OR TLR8 AND TLR2 AGONISTS | CAYLA (FR) | 2014-05-22 | — | — | US | disclosed |
| EP-2732825-A1 | Conjugated TLR7 and/or TLR8 and TLR2 agonists | Invivogen (FR) | 2014-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140141033-A1 | CONJUGATED TLR7 AND/OR TLR8 AND TLR2 AGONISTS | TLR7, TLR8, TLR9 | SMN1; SMN2 3974/4885CYP1A2 2817/4885CYP2C9 3545/4885 |
| US-20140242108-A1 | Conjugated TLR7 and/or TLR8 and TLR2 polycationic agonists | TLR7, TLR8, TLR9 | SMN1; SMN2 4596/4885CYP1A2 3277/4885CYP2C9 4100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.