Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1572510 | 0.87 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL1572886 | 0.85 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL1572885 | 0.85 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL1572054 | 0.83 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL982926 | 0.80 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL1764517 | 0.78 | KDM4E (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL1764519 | 0.78 | KDM4E (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL13254772 | 0.78 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL3412370 | 0.77 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL1572222 | 0.77 | HCRTR1 (0.63) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094690-B1 | 2-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-04-13 | — | — | EP | claimed |