SCHEMBL15733399

SCHEMBL15733399

CO[Si](C)(C)Cc1ccc(C(F)(F)F)cc1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.46
TAAR1 Q96RJ0 1/20 0.42
PYCR1 P32322 1/20 0.41
MAPK8 P45983 1/20 0.40
MAPK10 P53779 1/20 0.40
KMT2A Q03164 2/20 0.40
MAOB P27338 5/20 0.39
ALDH1A1 P00352 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15739086 0.89 IDO1 (0.46) IDO1TAAR1PYCR1KMT2AMAOB
SCHEMBL4811360 0.83 ESR1 (0.42) IDO1TAAR1
SCHEMBL15737362 0.82 IDO1 (0.47) IDO1TAAR1PYCR1KMT2AMAOB
SCHEMBL15736975 0.81 TAAR1 (0.48) IDO1TAAR1KMT2AMAOBMEN1
SCHEMBL15735273 0.81 IDO1 (0.43) IDO1TAAR1PYCR1KMT2AMAOB
SCHEMBL15738077 0.81 IDO1 (0.46) IDO1TAAR1PYCR1KMT2AMAOB
SCHEMBL15736555 0.81 IDO1 (0.46) IDO1
SCHEMBL15736026 0.79 IDO1 (0.44) IDO1TAAR1KMT2AMAOBALDH1A1
SCHEMBL15734264 0.79 IDO1 (0.44) IDO1TAAR1PYCR1KMT2AMAOB
SCHEMBL15737213 0.79 IDO1 (0.44) IDO1TAAR1MAPK8MAPK10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
CN-107141313-A Transparent oxide electrode and its production method that surface modifier, surface for transparent oxide electrode are modified 信越化学工业株式会社 2017-09-08 CN disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed