SCHEMBL1573489

SCHEMBL1573489

CCCCCCCCNc1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.52
ADRA2A P08913 2/20 0.52
ADORA3 P0DMS8 2/20 0.52
TACR2 P21452 2/20 0.52
SLC6A2 P23975 2/20 0.52
SLC6A4 P31645 2/20 0.52
SLC6A3 Q01959 2/20 0.52
ALDH1A1 P00352 2/20 0.52
HSD17B10 Q99714 2/20 0.52
KDM4E B2RXH2 1/20 0.52
LMNA P02545 1/20 0.52
SHBG P04278 1/20 0.52
TP53 P04637 1/20 0.52
CYP3A4 P08684 1/20 0.52
HSPD1 P10809 1/20 0.52
ADRB3 P13945 1/20 0.52
HTR2C P28335 1/20 0.52
HSPE1 P61604 1/20 0.52
HIF1A Q16665 1/20 0.52
TST Q16762 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1955160 1.00 ESR1 (0.52) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL1954253 1.00 ESR1 (0.52) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL10485907 1.00 ESR1 (0.52) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL1953530 1.00 ESR1 (0.52) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL7271147 1.00 ESR1 (0.52) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL7263389 1.00 ESR1 (0.52) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL1953355 1.00 ESR1 (0.52) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL7262799 1.00 ESR1 (0.52) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL7271241 1.00 ESR1 (0.52) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL1955070 1.00 ESR1 (0.52) ESR1ADRA2AADORA3TACR2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105648029-B A kind of energy resonance system and preparation method thereof of recognizable microfilament bacterium 天津城建大学 2019-06-11 CN claimed
CN-105648029-A Energy resonance system capable of recognizing microthrix parvicella and preparation method of energy resonance system 天津城建大学 2016-06-08 CN claimed
CN-115407622-A Negative photoresist developing solution and preparation method thereof 合肥中聚和成电子材料有限公司 2022-11-29 CN disclosed
EP-3838892-B1 METHOD FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2022-10-12 EP disclosed
US-11459427-B1 Synthesis of polyaniline or derivatives thereof KING ABDULAZIZ UNIVERSITY (SA) 2022-10-04 US disclosed
EP-3293173-B1 METHOD FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2021-07-28 EP disclosed
EP-3838892-A1 METHOD FOR PRODUCING ISOCYANATE Asahi Kasei Kabushiki Kaisha (JP) 2021-06-23 EP disclosed
EP-2980066-B1 METHOD FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2021-04-21 EP disclosed
CN-107266338-B The manufacturing method of isocyanates 旭化成株式会社 2019-10-11 CN disclosed
CN-105648029-B A kind of energy resonance system and preparation method thereof of recognizable microfilament bacterium 天津城建大学 2019-06-11 CN disclosed
EP-3153499-B1 METHOD FOR PRODUCING N-SUBSTITUTED CARBAMIC ACID ESTER ASAHI CHEMICAL IND (JP) 2018-09-19 EP disclosed
EP-0758450-B1 OPTICAL SENSOR FOR THE DETERMINATION OF IONS CIBA GEIGY AG (CH) 1998-08-05 EP disclosed
EP-0758450-A1 OPTICAL SENSOR FOR THE DETERMINATION OF IONS Novartis AG (CH) 1997-02-19 EP disclosed
WO-1995026501-A1 OPTICAL SENSOR FOR THE DETERMINATION OF IONS CIBA-GEIGY AG (CH) 1995-10-05 WO disclosed
EP-0623599-A1 Optical sensors for the determination of cations CIBA-GEIGY AG (CH) 1994-11-09 EP disclosed
US-5166350-A Process for the manufacture of fluoran compounds CIBA-GEIGY CORPORATION (US) 1992-11-24 US disclosed
US-4520134-A ANALGESICS ROSEN GERALD M (US) 1985-05-28 US disclosed
EP-0116637-A4 N-ALKYL-4'-HYDROXYACETANILIDES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND THEIR USE. ROSEN GERALD M 1985-02-18 EP disclosed
EP-0116637-A1 N-ALKYL-4'-HYDROXYACETANILIDES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND THEIR USE ROSEN, Gerald M. (US) 1984-08-29 EP disclosed
WO-1984000886-A1 N-ALKYL-4'-HYDROXYACETANILIDES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND THEIR USE ROSEN GERALD M 1984-03-15 WO disclosed