Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | HPGD | P15428 | 4/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.73 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498897 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL11563521 | 0.76 | KDM4E (0.73) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL154819 | 0.76 | KDM4E (0.73) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL14538334 | 0.76 | KDM4E (0.73) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL30492599 | 0.75 | CYP3A4 (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL1071454 | 0.75 | CYP3A4 (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL12655980 | 0.74 | KDM4E (0.77) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL9438481 | 0.74 | ADORA2A (0.54) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL9438558 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL1536347 | 0.73 | KDM4E (0.64) | KDM4EALDH1A1HPGDMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1548005-B1 | PROCESS FOR PRODUCING 2-SUBSTITUTED PYRIDINE DERIVATIVE | KURARAY CO (JP) | 2011-04-13 | — | — | EP | disclosed |
| US-7560563-B2 | Process for producing 2-substituted pyridine derivative | KURARAY CO., LTD. (JP) | 2009-07-14 | — | — | US | disclosed |
| US-20060041142-A1 | Process for producing 2-substituted pyridine derivative | KURARAY CO., LTD. (JP) | 2006-02-23 | — | — | US | disclosed |
| EP-1548005-A1 | PROCESS FOR PRODUCING 2-SUBSTITUTED PYRIDINE DERIVATIVE | Kuraray Co., Ltd. (JP) | 2005-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060041142-A1 | Process for producing 2-substituted pyridine derivative | IDH2, IDH1, NDUFS5 | KDM4E 323/4885ALDH1A1 950/4885HPGD 945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.