SCHEMBL15735869

SCHEMBL15735869

CCO[Si](C)(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.43
TACR1 P25103 13/20 0.36
ATM Q13315 1/20 0.35
NPSR1 Q6W5P4 1/20 0.33
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33
GPBAR1 Q8TDU6 1/20 0.33
CACNA1F O60840 1/20 0.33
CACNA1D Q01668 1/20 0.33
CACNA1S Q13698 1/20 0.33
CACNA1C Q13936 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15738291 0.86 IDO1 (0.43) IDO1TACR1ATMNPSR1HSP90AA1
SCHEMBL15733675 0.84 IDO1 (0.44) IDO1TACR1ATMHSP90AA1HSP90AB1
SCHEMBL15736113 0.83 IDO1 (0.49) IDO1
SCHEMBL15736868 0.83 IDO1 (0.41) IDO1TACR1ATMNPSR1HSP90AA1
SCHEMBL15735273 0.82 IDO1 (0.43) IDO1HSP90AA1
SCHEMBL15736555 0.81 IDO1 (0.46) IDO1TACR1ATMHSP90AA1HSP90AB1
SCHEMBL15738490 0.81 IDO1 (0.42) IDO1TACR1NPSR1HSP90AA1HSP90AB1
SCHEMBL15736378 0.80 IDO1 (0.39) IDO1TACR1ATM
SCHEMBL15734314 0.79 IDO1 (0.41) IDO1TACR1ATMHSP90AA1HSP90AB1
SCHEMBL15736230 0.79 IDO1 (0.38) IDO1TACR1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed