SCHEMBL15736705

SCHEMBL15736705

CO[Si](C)(C)Cc1cccc(C(F)(F)F)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.51
HTR2A P28223 2/20 0.50
HTR2B P41595 2/20 0.50
HTR2C P28335 1/20 0.50
TAAR1 Q96RJ0 1/20 0.49
ABHD6 Q9BV23 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ACP3 P15309 1/20 0.45
MAOB P27338 4/20 0.44
SLC6A4 P31645 2/20 0.44
SIGMAR1 Q99720 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
ADRA2C P18825 1/20 0.44
ADRA1A P35348 1/20 0.44
DRD3 P35462 1/20 0.44
OPRK1 P41145 1/20 0.44
MIF P14174 1/20 0.44
OPRM1 P35372 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15738828 0.90 IDO1 (0.51) IDO1HTR2AHTR2BHTR2CTAAR1
SCHEMBL15737995 0.85 IDO1 (0.53) IDO1HTR2AHTR2BHTR2CTAAR1
SCHEMBL15735511 0.84 TAAR1 (0.54) IDO1HTR2AHTR2BHTR2CTAAR1
SCHEMBL15736113 0.84 IDO1 (0.49) IDO1HTR2AHTR2BHTR2CTAAR1
SCHEMBL15736504 0.83 IDO1 (0.51) IDO1HTR2AHTR2BHTR2CTAAR1
SCHEMBL15736555 0.82 IDO1 (0.46) IDO1ABHD6SLC6A4
SCHEMBL15737554 0.82 IDO1 (0.50) IDO1HTR2AHTR2BHTR2CTAAR1
SCHEMBL15735140 0.82 IDO1 (0.50) IDO1HTR2AHTR2BHTR2CTAAR1
SCHEMBL15734785 0.82 IDO1 (0.50) IDO1HTR2AHTR2BHTR2CTAAR1
SCHEMBL15735816 0.81 TAAR1 (0.51) IDO1HTR2AHTR2BHTR2CTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
CN-107141313-A Transparent oxide electrode and its production method that surface modifier, surface for transparent oxide electrode are modified 信越化学工业株式会社 2017-09-08 CN disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed