SCHEMBL15736740

SCHEMBL15736740

CC(C)OC(CCCCc1ccc(C(F)(F)F)cc1)(O[SiH3])OC(C)C

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
GAA P10253 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
FDFT1 P37268 2/20 0.38
KCNH2 Q12809 1/20 0.37
TMEM97 Q5BJF2 1/20 0.37
MAOB P27338 2/20 0.36
ALDH1A1 P00352 1/20 0.36
IDO1 P14902 2/20 0.36
PTPN2 P17706 1/20 0.36
PTPN1 P18031 1/20 0.36
PTPN6 P29350 1/20 0.36
PTPN11 Q06124 1/20 0.36
MIF P14174 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15738546 0.99 HDAC1 (0.40) HDAC1HDAC8TAAR1GAAMEN1
SCHEMBL15737376 0.99 HDAC1 (0.40) HDAC1HDAC8TAAR1GAAMEN1
SCHEMBL15735098 0.97 TAAR1 (0.40) HDAC1HDAC8TAAR1GAAMEN1
SCHEMBL15737270 0.91 TAAR1 (0.42) TAAR1MEN1KMT2AFDFT1KCNH2
SCHEMBL15737205 0.86 TACR1 (0.36) MEN1KMT2AIDO1
SCHEMBL15737277 0.85 TAAR1 (0.35) TAAR1GAAMEN1KMT2AKCNH2
SCHEMBL15733978 0.84 TACR1 (0.35) MEN1KMT2AIDO1
SCHEMBL15736775 0.84 TACR1 (0.35) MEN1KMT2AIDO1
SCHEMBL15735000 0.84 TAAR1 (0.34) TAAR1GAAMEN1KMT2A
SCHEMBL15738094 0.84 TAAR1 (0.34) TAAR1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed