SCHEMBL15738014

SCHEMBL15738014

CO[Si](O)(O)CCCc1cc(F)cc(F)c1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.34
TRPV1 Q8NER1 1/20 0.33
NOS3 P29474 2/20 0.31
NOS1 P29475 2/20 0.31
NOS2 P35228 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
AKR1B10 O60218 1/20 0.30
AKR1B1 P15121 1/20 0.30
CYP4F2 P78329 1/20 0.30
CYP4A11 Q02928 1/20 0.30
CYP17A1 P05093 1/20 0.30
CYP21A2 P08686 1/20 0.30
CYP11B1 P15538 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15736561 0.95 TRPV1 (0.35) IDO1TRPV1NOS3NOS1NOS2
SCHEMBL15735385 0.93 TRPV1 (0.34) IDO1TRPV1NOS3NOS1NOS2
SCHEMBL15738618 0.93 TRPV1 (0.34) IDO1TRPV1NOS3NOS1NOS2
SCHEMBL15735694 0.89 IDO1 (0.36) IDO1MEN1KMT2ACYP4F2CYP4A11
SCHEMBL15733465 0.86 IDO1 (0.34) IDO1TRPV1NOS3NOS1NOS2
SCHEMBL15738326 0.84 MAOB (0.33) NOS3NOS1NOS2TNKS2CYP4F2
SCHEMBL15737190 0.83 TAAR1 (0.46) IDO1
SCHEMBL15734154 0.82 TAAR1 (0.40) KMT2A
SCHEMBL15733506 0.81 IDO1 (0.36) IDO1TRPV1NOS3NOS1NOS2
SCHEMBL15735166 0.81 TRPV1 (0.35) IDO1TRPV1NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed