⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17178460 | 1.00 | — | — | |
| SCHEMBL15740210 | 0.79 | — | — | |
| SCHEMBL19372789 | 0.77 | — | — | |
| SCHEMBL15718077 | 0.77 | — | — | |
| SCHEMBL7099671 | 0.75 | MAPT (0.31) | — | |
| SCHEMBL15740154 | 0.73 | — | — | |
| SCHEMBL15740204 | 0.71 | — | — | |
| SCHEMBL15719022 | 0.71 | MAPT (0.32) | — | |
| SCHEMBL15740105 | 0.70 | — | — | |
| SCHEMBL19664244 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3251674-A2 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | BioCryst Pharmaceuticals, Inc. (US) | 2017-12-06 | — | — | EP | disclosed |
| WO-2014078778-A2 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | BIOCRYST PHARMACEUTICALS, INC. (US) | 2014-05-22 | — | — | WO | disclosed |