Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | SLC16A3 | O15427 | 7/20 | 0.66 |
| ▸ | SLC16A1 | P53985 | 7/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740335 | 1.00 | KDM4E (1.00) | KDM4EKMT2ALMNAPKMSLC16A3 | |
| SCHEMBL7814195 | 0.87 | KDM4E (0.76) | KDM4EKMT2ALMNAPKMSLC16A3 | |
| SCHEMBL7814194 | 0.87 | KDM4E (0.76) | KDM4EKMT2ALMNAPKMSLC16A3 | |
| SCHEMBL28436908 | 0.86 | KDM4E (0.76) | KDM4EKMT2ALMNAPKMSLC16A3 | |
| SCHEMBL21457552 | 0.86 | ADORA2A (0.77) | KDM4EKMT2ALMNAPKMSLC16A3 | |
| SCHEMBL21457548 | 0.86 | ADORA2A (0.77) | KDM4EKMT2ALMNAPKMSLC16A3 | |
| SCHEMBL27096569 | 0.85 | KDM4E (0.74) | KDM4EKMT2ALMNAPKMSLC16A3 | |
| SCHEMBL9147405 | 0.84 | KDM4E (0.73) | KDM4EKMT2ALMNAPKMSLC16A3 | |
| SCHEMBL9789047 | 0.84 | KDM4E (0.78) | KDM4EKMT2ALMNAPKMSLC16A3 | |
| SCHEMBL9789045 | 0.84 | KDM4E (0.78) | KDM4EKMT2ALMNAPKMSLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014081856-A2 | LIGANDS THAT TARGET HCV-E2 BINDING SITES ON CD81 AND THERAPEUTIC METHODS USING THEM | AZZAZY HASSAN (EG) | 2014-05-30 | — | — | WO | disclosed |