Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2765256 | 1.00 | FUCA1 (0.56) | FUCA1SIGMAR1S1PR1S1PR5DPP4 | |
| SCHEMBL2764614 | 1.00 | FUCA1 (0.56) | FUCA1SIGMAR1S1PR1S1PR5DPP4 | |
| SCHEMBL4089384 | 0.89 | FUCA1 (0.50) | FUCA1SIGMAR1S1PR1S1PR5DPP4 | |
| SCHEMBL16759827 | 0.87 | FUCA1 (0.64) | FUCA1SIGMAR1S1PR1S1PR5GBA1 | |
| SCHEMBL16775256 | 0.87 | FUCA1 (0.64) | FUCA1SIGMAR1S1PR1S1PR5GBA1 | |
| SCHEMBL24893928 | 0.85 | FUCA1 (0.46) | FUCA1SIGMAR1S1PR1S1PR5DPP4 | |
| SCHEMBL19327458 | 0.83 | FUCA1 (0.60) | FUCA1SIGMAR1S1PR1S1PR5DPP4 | |
| SCHEMBL5836807 | 0.83 | FUCA1 (0.60) | FUCA1SIGMAR1S1PR1S1PR5DPP4 | |
| SCHEMBL7575241 | 0.83 | FUCA1 (0.60) | FUCA1SIGMAR1S1PR1S1PR5DPP4 | |
| SCHEMBL1088536 | 0.83 | FUCA1 (0.60) | FUCA1SIGMAR1S1PR1S1PR5DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140085-B1 | AZABICYCLOALKANES AS CCR5 MODULATORS | PHIVCO UK LTD (GB) | 2011-04-13 | — | — | EP | disclosed |
| US-6586430-B1 | Administering azabicyclo compounds to treat human immunodeficiency virus infections and respiratory system disorders | PFIZER INC. | 2003-07-01 | — | — | US | disclosed |
| EP-1140085-A1 | AZABICYCLOALKANES AS CCR5 MODULATORS | Pfizer Limited (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000038680-A1 | AZABICYCLOALKANES AS CCR5 MODULATORS | PFIZER LIMITED (GB) | 2000-07-06 | — | — | WO | disclosed |