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Sugi Predict / Compounds / SCHEMBL15744315

SCHEMBL15744315

SCHEMBL15744315

CCCc1ccc(-c2ccc(-c3cc(F)c(C(F)(F)OC(F)(F)F)c(F)c3)c(F)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RARB P10826 3/20 0.38
▸ RARA P10276 1/20 0.38
▸ RARG P13631 1/20 0.38
▸ MCL1 Q07820 1/20 0.35
▸ KIF11 P52732 1/20 0.35
▸ S1PR1 P21453 3/20 0.34
▸ S1PR3 Q99500 2/20 0.34
▸ PDK2 Q15119 1/20 0.33
▸ MAOB P27338 2/20 0.33
▸ NPC1 O15118 2/20 0.33
▸ RAB9A P51151 2/20 0.33
▸ TP53 P04637 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ TAAR1 Q96RJ0 1/20 0.33
▸ GRM2 Q14416 1/20 0.32
▸ CYP17A1 P05093 1/20 0.32
▸ ALOX5 P09917 1/20 0.31
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15744475 1.00 RARB (0.38) RARBRARARARGMCL1KIF11
SCHEMBL15745167 0.95 RARB (0.36) RARBRARARARGMCL1KIF11
SCHEMBL15745124 0.93 GRM2 (0.35) RARBRARARARGMCL1KIF11
SCHEMBL15744321 0.93 GRM2 (0.35) RARBRARARARGMCL1KIF11
SCHEMBL15744304 0.92 PDK2 (0.37) RARBS1PR1S1PR3PDK2NPC1
SCHEMBL15744316 0.90 RARB (0.39) RARBRARARARGMCL1KIF11
SCHEMBL15744349 0.90 RARB (0.39) RARBRARARARGMCL1KIF11
SCHEMBL15744374 0.90 RARB (0.39) RARBRARARARGMCL1KIF11
SCHEMBL15745047 0.90 GRM2 (0.39) RARBRARARARGS1PR1S1PR3
SCHEMBL19775414 0.90 RARB (0.38) RARBRARARARGMCL1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9487703-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-11-08 — — US disclosed
US-9487703-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-11-08 — — US disclosed
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 — — US disclosed
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 — — US disclosed
US-20150166891-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-06-18 — — US disclosed
US-20150166891-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-06-18 — — US disclosed
EP-2735599-B1 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORP (JP) 2015-04-29 — — EP disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 — — US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 — — US disclosed
EP-2735599-A1 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC Corporation (JP) 2014-05-28 — — EP disclosed