SCHEMBL15744360

SCHEMBL15744360

CCCc1ccc(C(F)(F)Oc2ccc(-c3cc(F)c(C(F)(F)OC(F)(F)F)c(F)c3)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.34
PPARD Q03181 2/20 0.33
PPARA Q07869 2/20 0.33
PPARG P37231 1/20 0.33
RARB P10826 3/20 0.33
RARA P10276 2/20 0.33
RARG P13631 1/20 0.33
THRB P10828 1/20 0.32
SERPINE1 P05121 2/20 0.32
PRMT6 Q96LA8 1/20 0.32
ACACB O00763 1/20 0.31
ACACA Q13085 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
DAO P14920 1/20 0.30
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15744915 0.95 MAOB (0.34) MAOBPPARDPPARAPPARGRARB
SCHEMBL15744793 0.93 MAOB (0.35) MAOBRARBRARARARGTHRB
SCHEMBL7731652 0.91 MAOB (0.39) MAOBPPARDPPARAPPARGRARB
SCHEMBL15744512 0.90 GRM2 (0.38) MAOBRARBRARARARG
SCHEMBL15745194 0.90 MAOB (0.32) MAOBRARBRARARARG
SCHEMBL15744313 0.89 RARB (0.34) MAOBRARBRARARARGTHRB
SCHEMBL15744500 0.89 RARB (0.34) MAOBRARBRARARARGTHRB
SCHEMBL15744316 0.89 RARB (0.39) MAOBRARBRARARARGTHRB
SCHEMBL15744349 0.89 RARB (0.39) MAOBRARBRARARARGTHRB
SCHEMBL15744374 0.89 RARB (0.39) MAOBRARBRARARARGTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
EP-2735599-A1 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC Corporation (JP) 2014-05-28 EP disclosed