SCHEMBL15744369

SCHEMBL15744369

CCCC1CCC(C(F)(F)Oc2ccc(-c3cc(F)c(C(F)(F)OC(F)(F)F)c(F)c3)c(F)c2)CC1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 2/20 0.35
ALOX5AP P20292 1/20 0.33
FEN1 P39748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745025 0.97 GRM2 (0.33) GRM2ALOX5APFEN1
SCHEMBL15745072 0.90 GRM2 (0.31) GRM2
SCHEMBL15744230 0.90 GRM2 (0.31) GRM2
SCHEMBL15744972 0.89 GRM2 (0.32) GRM2
SCHEMBL14226654 0.89 GRM2 (0.32) GRM2ALOX5APFEN1
SCHEMBL15744469 0.89 CHRM2 (0.32)
SCHEMBL13002934 0.88 ALOX5AP (0.36) GRM2ALOX5APFEN1
SCHEMBL15744322 0.86 CHRM2 (0.31)
SCHEMBL15745001 0.85 PDK2 (0.39)
SCHEMBL15744465 0.85 GRM2 (0.37) GRM2ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
EP-2735599-A1 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC Corporation (JP) 2014-05-28 EP disclosed