Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 3/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84043 | 0.82 | PDE2A (0.53) | PTPN5CYP2D6CYP2C9HIF1APDE2A | |
| SCHEMBL12629913 | 0.80 | PTPN5 (0.48) | PTPN5CYP2D6CYP2C9HIF1APDE2A | |
| SCHEMBL14407076 | 0.80 | PTPN5 (0.48) | PTPN5CYP2D6CYP2C9HIF1APDE2A | |
| Ammonia Solution, Strong SCHEMBL27642816 | 0.80 | PDE2A (0.52) | PTPN5CYP2D6CYP2C9HIF1APDE2A | |
| SCHEMBL1538742 | 0.79 | CYP2C9 (0.50) | PTPN5CYP2D6CYP2C9HIF1APDE2A | |
| SCHEMBL24408943 | 0.78 | PTPN5 (0.47) | PTPN5CYP2D6CYP2C9HIF1APDE2A | |
| SCHEMBL24736871 | 0.78 | PTPN5 (0.47) | PTPN5CYP2D6CYP2C9HIF1APDE2A | |
| SCHEMBL22242853 | 0.78 | PTPN5 (0.47) | PTPN5CYP2D6CYP2C9HIF1APDE2A | |
| SCHEMBL16105865 | 0.78 | ESR1 (0.50) | PTPN5CYP2D6CYP2C9HIF1APDE2A | |
| SCHEMBL25467240 | 0.78 | PTPN5 (0.47) | PTPN5CYP2D6CYP2C9HIF1APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2735599-B1 | Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device | JNC CORP (JP) | 2015-04-29 | — | — | EP | disclosed |
| EP-2735599-A1 | Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device | JNC Corporation (JP) | 2014-05-28 | — | — | EP | disclosed |