SCHEMBL15746110

SCHEMBL15746110

Cc1ccc(Oc2ccc(-c3ccc(Oc4ccc(N5C(=O)C6C7C=CC(C6C5=O)C5C(=O)N(c6ccc(Oc8ccc(C(C)(C)c9ccc(Oc%10ccc(N%11C(=O)C%12C%13C=CC(C%14C(=O)N(C)C(=O)C%13%14)C%12C%11=O)cc%10)cc9)cc8)cc6)C(=O)C75)cc4)cc3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
TP53 P04637 1/20 0.39
LMNA P02545 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GAA P10253 1/20 0.36
ADCY2 Q08462 3/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MAPT P10636 3/20 0.33
CACNA1B Q00975 2/20 0.33
APBA1 Q02410 2/20 0.33
HPGD P15428 2/20 0.33
HTT P42858 1/20 0.33
ATM Q13315 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6365242 0.97 TP53 (0.41) ALDH1A1TP53LMNASMN1; SMN2GAA
SCHEMBL15746109 0.97 TP53 (0.41) ALDH1A1TP53LMNASMN1; SMN2GAA
SCHEMBL14076704 0.97 TP53 (0.41) ALDH1A1TP53LMNASMN1; SMN2GAA
SCHEMBL13773285 0.90 TP53 (0.42) ALDH1A1TP53LMNASMN1; SMN2GAA
SCHEMBL13400450 0.88 TP53 (0.48) ALDH1A1TP53LMNASMN1; SMN2GAA
SCHEMBL13855439 0.86 TSHR (0.34) ALDH1A1TP53LMNASMN1; SMN2ADCY2
SCHEMBL14005780 0.84 SMN1; SMN2 (0.37) ALDH1A1TP53LMNASMN1; SMN2ADCY2
SCHEMBL13855427 0.84 TP53 (0.46) ALDH1A1TP53LMNASMN1; SMN2GAA
SCHEMBL13855431 0.84 TP53 (0.51) ALDH1A1TP53LMNAGAAMEN1
SCHEMBL12589254 0.84 SMN1; SMN2 (0.42) ALDH1A1TP53LMNASMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9331280-B2 Transparent electrochromic polyimide, method for manufacturing the same, and electrochromic device utilizing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2016-05-03 US disclosed
US-20140146380-A1 TRANSPARENT ELECTROCHROMIC POLYIMIDE, METHOD FOR MANUFACTURING THE SAME, AND ELECTROCHROMIC DEVICE UTILIZING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2014-05-29 US disclosed