Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | FECH | P22830 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | MELK | Q14680 | 1/20 | 0.45 |
| ▸ | MYLK3 | Q32MK0 | 1/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.45 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.45 |
| ▸ | TP53RK | Q96S44 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747791 | 0.92 | MTOR (0.61) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL15747847 | 0.87 | MTOR (0.69) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL15747752 | 0.86 | MTOR (0.69) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL15747878 | 0.85 | MTOR (0.71) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL16748363 | 0.85 | MTOR (0.72) | MTORPIK3CAATMATR | |
| SCHEMBL16748265 | 0.85 | MTOR (0.72) | MTORPIK3CAATMATR | |
| SCHEMBL31439341 | 0.85 | MTOR (0.60) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL15747877 | 0.84 | MTOR (0.77) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL15747862 | 0.84 | MTOR (0.78) | MTORPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL31439313 | 0.83 | MTOR (0.64) | MTORPIK3CAPIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014079364-A1 | IMIDAZOLONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 北京富龙康泰生物技术有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |