Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.54 |
| ▸ | ATR | Q13535 | 3/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 17/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.53 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | FECH | P22830 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | MELK | Q14680 | 1/20 | 0.48 |
| ▸ | MYLK3 | Q32MK0 | 1/20 | 0.48 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.48 |
| ▸ | TP53RK | Q96S44 | 1/20 | 0.48 |
| ▸ | PIK3C2A | O00443 | 2/20 | 0.47 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747838 | 0.93 | MTOR (0.59) | ATMATRKCNH2MTORPIK3CA | |
| SCHEMBL15747791 | 0.88 | MTOR (0.61) | ATMATRMTORPIK3CAPIK3CD | |
| SCHEMBL15747793 | 0.86 | MTOR (0.56) | ATMATRKCNH2MTORPIK3CA | |
| SCHEMBL15747806 | 0.85 | MTOR (0.65) | ATMATRMTORPIK3CAPIK3CD | |
| SCHEMBL15747859 | 0.83 | MTOR (0.50) | ATMATRKCNH2MTORPIK3CA | |
| SCHEMBL15747875 | 0.82 | MTOR (0.51) | ATMATRMTORPIK3CAPIK3CD | |
| SCHEMBL15747891 | 0.82 | MTOR (0.51) | ATMATRMTORPIK3CAPIK3CD | |
| SCHEMBL15747819 | 0.82 | MTOR (0.61) | ATMATRMTORPIK3CAPIK3CD | |
| SCHEMBL15747781 | 0.81 | ATM (0.59) | ATMATRMTORPIK3CAPIK3CD | |
| SCHEMBL15747784 | 0.80 | MTOR (0.61) | ATMATRMTORPIK3CAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014079364-A1 | IMIDAZOLONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 北京富龙康泰生物技术有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |