SCHEMBL15748490

SCHEMBL15748490

c1ccc(-c2ccc3c(c2)c2cc(-c4ccc(-c5ccc6c(c5)c5ccccc5n6-c5cc(-c6ccccc6)nc(-c6ccccc6)n5)cc4)ccc2n3-c2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
ATM Q13315 1/20 0.45
MAPT P10636 5/20 0.44
MAPK1 P28482 4/20 0.44
TSHR P16473 2/20 0.44
HSD17B10 Q99714 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HPGD P15428 4/20 0.43
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
ALDH1A1 P00352 3/20 0.39
NTSR1 P30989 1/20 0.39
PTGER4 P35408 1/20 0.39
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
TSPO P30536 1/20 0.36
LMNA P02545 2/20 0.35
HTT P42858 1/20 0.35
GLA P06280 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17228142 1.00 KDM4E (0.45) KDM4EL3MBTL1ATMMAPTMAPK1
SCHEMBL16234030 1.00 KDM4E (0.45) KDM4EL3MBTL1ATMMAPTMAPK1
SCHEMBL16234058 1.00 KDM4E (0.45) KDM4EL3MBTL1ATMMAPTMAPK1
SCHEMBL15197795 1.00 KDM4E (0.45) KDM4EL3MBTL1ATMMAPTMAPK1
SCHEMBL6375115 1.00 KDM4E (0.45) KDM4EL3MBTL1ATMMAPTMAPK1
SCHEMBL6372987 0.99 KDM4E (0.46) KDM4EL3MBTL1ATMMAPTMAPK1
SCHEMBL15371728 0.99 KDM4E (0.46) KDM4EL3MBTL1ATMMAPTMAPK1
SCHEMBL15394905 0.97 KDM4E (0.45) KDM4EL3MBTL1ATMMAPTMAPK1
SCHEMBL6372983 0.97 MAPT (0.44) KDM4EL3MBTL1ATMMAPTMAPK1
SCHEMBL11998173 0.96 KDM4E (0.42) KDM4EL3MBTL1ATMMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014081206-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2014-05-30 WO disclosed