SCHEMBL15748613

SCHEMBL15748613

Cc1cc(C)cc(C2C=Cc3ccccc3N2)c1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NPC1 O15118 1/20 0.34
HPN P05981 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
PBRM1 Q86U86 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8558204 0.80 MAPT (0.41) GAAMAPTMEN1KMT2ANPC1
SCHEMBL14979068 0.78 KMT2A (0.34) GAAMAPTMEN1KMT2ANPC1
SCHEMBL21539395 0.75 PBRM1 (0.40) GAAMEN1KMT2ANPC1HPN
SCHEMBL4287850 0.75 KMT2A (0.41) GAAMAPTMEN1KMT2A
SCHEMBL17634322 0.75 KMT2A (0.41) GAAMAPTMEN1KMT2ATNKS2
SCHEMBL30695372 0.75 PBRM1 (0.41) GAAMAPTMEN1KMT2ANPC1
SCHEMBL18562458 0.74 MEN1 (0.45) GAAMAPTMEN1KMT2ANPC1
SCHEMBL31265309 0.73 GAA (0.32) GAAMAPT
SCHEMBL31492171 0.72 GAA (0.32) GAAMAPT
SCHEMBL31265316 0.72 GAA (0.32) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015093814-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-06-25 WO disclosed
WO-2014081206-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2014-05-30 WO disclosed