⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5835905 | 0.86 | — | — | |
| SCHEMBL17696624 | 0.84 | MAPT (0.35) | — | |
| SCHEMBL15748583 | 0.84 | — | — | |
| SCHEMBL15748606 | 0.84 | — | — | |
| SCHEMBL22815111 | 0.84 | — | — | |
| SCHEMBL17192518 | 0.81 | MAPT (0.36) | — | |
| SCHEMBL15748641 | 0.80 | MAPT (0.32) | — | |
| SCHEMBL15748024 | 0.80 | PLG (0.33) | — | |
| SCHEMBL15750084 | 0.80 | — | — | |
| SCHEMBL15748076 | 0.80 | MAPT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014081300-A1 | CHANNEL PROTEIN ACTIVATABLE LIPOSOMES | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2014-05-30 | — | — | WO | disclosed |
| WO-2014081303-A1 | CHEMICALLY CLEAVABLE GROUP | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2014-05-30 | — | — | WO | disclosed |