SCHEMBL15748645

SCHEMBL15748645

CNC(=O)OC1/C=C/C(OC(N)=O)CCC(O)C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22821418 1.00 CHRM1 (0.31) CHRM1
SCHEMBL15747935 0.92 CHRM1 (0.35) CHRM1
SCHEMBL23636389 0.87
SCHEMBL25668231 0.85
SCHEMBL17304949 0.85 CHRM1 (0.33) CHRM1
SCHEMBL23636370 0.84 CHRM1 (0.31) CHRM1
SCHEMBL15747971 0.83 CHRM1 (0.33) CHRM1
SCHEMBL23636390 0.83 CHRM1 (0.30) CHRM1
SCHEMBL15750245 0.83 EPHX1 (0.42) CHRM1
SCHEMBL17192567 0.82 BCHE (0.31) CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2709667-B1 BIO-ORTHOGONAL DRUG ACTIVATION TAGWORKS PHARMACEUTICALS B V (NL) 2022-04-13 EP disclosed
WO-2014081300-A1 CHANNEL PROTEIN ACTIVATABLE LIPOSOMES TAGWORKS PHARMACEUTICALS B.V. (NL) 2014-05-30 WO disclosed
WO-2014081303-A1 CHEMICALLY CLEAVABLE GROUP TAGWORKS PHARMACEUTICALS B.V. (NL) 2014-05-30 WO disclosed